Cloprostenol is used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (±)-Cloprostenol sodium salt is manufactured at Cayman Pharma, our Czech subsidiary. GMP material, which conforms to the USP and BVP Monographs, is available. The DMF is on file with the US FDA, Canada, Russia, in almost all EU member states, and in many other countries.